Gene Expression Subtyping Reveals Immune alterations:TCGA Database for Prognosis in Ovarian Serous Cystadenocarcinoma

Serous ovarian cancer is the most common and primary death type in cancer. In recent studies, tumor microenvironment immune infiltration significantly affect prognosis of This study analyzed four gene expression types TCGA database to extract differentially expressed genes verify prognostic significance. Meanwhile, functional enrichment protein interaction network analysis exposed that these were related response infiltration. Subsequently, we proved an independent data set from GEO database. Finally, multivariate cox regression revealed significance TAP1 CXCL13. The genetic alteration two shown. Then, established a nomogram model clinical risk factors. performed well Calibration plot Decision Curve Analysis. conclusion, have obtained list with better for serous cancer, based on this, tried establish model.